Inoue Lab


Department of Life Science and Medical Bioscience
School of Advanced Science and Engineering
Faculty of Science and Engineering
Waseda University
 日本語






 internal site


Publication

  1. Yoshiki Hatashita, Binglun Li, Mitsue Hagihara, Fumio Matsuzaki, Kazunari Miyamichi, Takafumi Inoue
    Cortical laminar organization of neuron-to-astrocyte connections revealed by transsynaptic tracing
    preprint: Sneak Peek; doi:10.2139/ssrn.4592585
  2. Katsuhiko Kunitake, Norio Motohashi, Takafumi Inoue, Yutaka Suzuki, Yoshitsugu Aoki
    Characterization of CD90/Thy-1 as a crucial molecular signature for myogenic differentiation in human urine-derived cells through single-cell RNA sequencing
    Scientific Reports, in press
  3. Yoshiki Hatashita, Zhaofa Wu, Hirotaka Fujita, Takuma Kumamoto, Jean Livet, Yulong Li, Manabu Tanifuji, Takafumi Inoue
    Spontaneous and multifaceted ATP release from astrocytes at the scale of hundreds of synapses
    GLIA, 71:2250-2265 (2023), doi:10.1002/glia.24392,  full text, preprint: bioRxiv; doi:10.1101/2022.12.05.519082
  4. Hirotaka Fujita, Chihiro Adachi, Takafumi Inoue
    Cholesterol-load evokes robust calcium response in macrophages: an early event toward cholesterol-induced macrophage death
    Cell Calcium, 113:102754 (2023), doi:10.1016/j.ceca.2023.102754
  5. Chihiro Adachi, Shio Otsuka, Takafumi Inoue
    Cholesterol-induced robust Ca oscillation in astrocytes required for survival and lipid droplet formation in high-cholesterol condition
    iScience, 25:105138 (2022), doi:10.1016/j.isci.2022.105138
  6. Miyuki Takahashi, Takeru Nakabayashi, Naoki Mita, Xiaohua Jin, Yuta Aikawa, Kodai Sasamoto, Goichi Miyoshi, Mariko Miyata, Takafumi Inoue, Toshio Ohshima
    Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons
    Molecular Brain, 15:37 (2022), doi:10.1186/s13041-022-00922-x
  7. Yuki Yamazaki, Maho Moizumi, Jun Nagai, Yoshiki Hatashita, Tianhong Cai, Papachan Kolattukudy, Takafumi Inoue, Yoshio Goshima, Toshio Ohshima
    Requirement of CRMP2 phosphorylation in neuronal migration of developing mouse cerebral cortex and hippocampus and redundant roles of CRMP1 and CRMP4
    Cerebral Cortex, 32:520-527 (2021), doi:10.1093/cercor/bhab228
  8. Hefei Guan, Steven J. Middleton, Takafumi Inoue, Thomas J. McHugh
    Lateralization of CA1 assemblies in the absence of CA3 input
    Nature Communications, 12:6114 (2021), doi:10.1038/s41467-021-26389-3
  9. Toma Adachi, Satoshi Miyashita, Mariko Yamashita, Mana Shimoda, Konstantin Okonechnikov, Lukas Chavez, Marcel Kool, Stefan M. Pfister, Takafumi Inoue, Daisuke Kawauchi, Mikio Hoshino
    Notch signaling between cerebellar granule cell progenitors
    eNeuro,  ENEURO.0468-20.2021 (2021), doi:10.1523/ENEURO.0468-20.2021
  10. Haruki Odaka, Tadahiro Numakawa, Minami Soga, Jun Kido, Shiro Matsumoto, Ryutaro Kajihara, Toshika Okumiya, Naoki Tani, Yuki Tanoue, Takaichi Fukuda, Hirokazu Furuya, Takafumi Inoue, Takumi Era
    An iPSC-based neural model of sialidosis uncovers glycolytic impairment-causing presynaptic dysfunction and deregulation of Ca2+ dynamics
    Neurobiology of Disease, 152:105279 (2021), doi:10.1016/j.nbd.2021.105279
  11. Kazuya Kuboyama, Takafumi Inoue, Yuki Hashimotodani, Takuya Itoh, Tohsuke Suzuki, Aya Tetsuzawa, Yosuke Ohtsuka, Ryo Kinoshita, Ren Takara, Tohru Miyazawa, Pooja Gusain, Masanobu Kano, Maki Yamada
    Traceable stimulus-dependent rapid molecular changes in dendritic spines in the brain
    Scientific Reports, 10:15266 (2020), doi:10.1038/s41598-020-72248-4, press release
  12. Jo Soo Hyun, Takafumi Inoue, Akiko Hayashi-Takagi
    Multi-scale understanding of NMDA receptor function in schizophrenia
    Biomolecules, 10:1172 (2020), doi:10.3390/biom10081172
  13. Li Binglun, Mariya Chavarha, Yuho Kobayashi, Satoshi Yoshinaga, Kazunori Nakajima, Michael Z. Lin, Takafumi Inoue
    Two-photon voltage imaging of spontaneous activity from multiple neurons reveals network activity in brain tissue
    iScience, 23:101363 (2020), doi:10.1016/j.isci.2020.101363
  14. Yuka Kuroiwa, Jun Nakayama, Chihiro Adachi, Takafumi Inoue, Shinya Watanabe, Kentaro Semba
    Proliferative classification of intracranially injected HER2-positive breast cancer cell lines
    Cancers, 12:1811 (2020), doi:10.3390/cancers12071811
  15. Hirotaka Fujita, Ryota Oikawa, Mayu Hayakawa, Fumiaki Tomoike, Yasuaki Kimura, Hiroyuki Okuno, Yoshiki Hatashita, Carolina Fiallos Oliveros, Haruhiko Bito, Toshio Ohshima, Satoshi Tsuneda, Hiroshi Abe, Takafumi Inoue
    Quantification of native mRNA dynamics in living neurons using fluorescence correlation spectroscopy and reduction-triggered fluorescent probes
    Journal of Biological Chemistry, 295:7923-7940 (2020), doi:10.1074/jbc.RA119.010921, preprint
  16. Hiroko Bannai, Takafumi Inoue, Matsumi Hirose, Fumihiro Niwa, Katsuhiko Mikoshiba
    Synaptic function and neuropathological disease revealed by quantum dot-single-particle tracking
    Neuromethods, 154:131-155 (2020), Chapter 7 in "Single Molecule Microscopy" Yamamoto N and Okada Y eds., doi:10.1007/978-1-0716-0532-5_7
  17. Chihiro Adachi, Naoto Kakinuma, Soohyun Jo, Takayuki Ishii, Yusuke Arai, Satoshi Arai, Tetsuya Kitaguchi, Sen Takeda, Takafumi Inoue
    Sonic hedgehog enhances calcium oscillations in hippocampal astrocytes
    Journal of Biological Chemistry, 294:16034-16048 (2019), doi:10.1074/jbc.RA119.007883, preprint
  18. Hideaki Kubotera, Hiroko Ikeshima-Kataoka, Yoshiki Hatashita, Anna Letizia Allegra Mascaro, Francesco Pavone, Takafumi Inoue
    Astrocytic endfeet re-cover blood vessels after removal by laser ablation
    Scientific Reports, 9:1263 (2019), doi:10.1038/s41598-018-37419-4 
  19. Takafumi Inoue
    TI Workbench, an integrated software package for electrophysiology and imaging
    Microscopy, 67:129-143 (2018), doi:10.1093/jmicro/dfy015, preprint
  20. Morteza Heidarinejad, Hideki Nakamura, Takafumi Inoue
    Stimulation-induced changes in diffusion and structure of calmodulin and calmodulin-dependent protein kinase II proteins in neurons
    Neuroscience Research, 136:13-32 (2018), doi:10.1016/j.neures.2018.01.003, postprint
  21. Bozong Xu, Ayumi Kumazawa, Shunsuke Kobayashi, Shin-ichi Hisanaga, Takafumi Inoue, Toshio Ohshima
    Cdk5 activity is required for Purkinje cell dendritic growth in cell-autonomous and non-cell-autonomous manners
    Developmental Neurobiology, 77:1175-1187 (2017), doi:10.1002/dneu.22507
  22. Kaori Kanemaru, Yoshikazu Nakamura, Kengo Totoki, Takatsugu Fukuyama, Madoka Shoji, Hisae Kaneko, Kanako Shiratori, Atsuko Yoneda, Takafumi Inoue, Yoichiro Iwakura, Kenji Kabashima, Kiyoko Fukami
    Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity
    Cell Death and Differentiation, 24:1079-1090 (2017), doi:10.1038/cdd.2017.56
  23. Masaru Ishibashi, Iryna Gumenchuk, Kenichi Miyazaki, Takafumi Inoue, William N. Ross, Christopher S. LeonardAccess the recommendation on F1000Primeß
    Hypocretin/orexin peptides alter spike-encoding by serotonergic dorsal raphe neurons through two distinct mechanisms that increase the late afterhyperpolarization
    The Journal of Neuroscience, 36:10097-10115 (2016), doi:10.1523/JNEUROSCI.0635-16.2016, pmid:27683906
  24. Haruki Odaka, Tadahiro Numakawa, Aya Yoshimura, Shingo Nakajima, Naoki Adachi, Yoshiko Ooshima, Takafumi Inoue, Hiroshi Kunugi
    Chronic glucocorticoid exposure suppressed the differentiation and survival of embryonic neural stem cells: possible involvement of ERK and PI3K/Akt signaling in the neuronal differentiation
    Neuroscience Research, 113:28-36 (2016), doi:10.1016/j.neures.2016.07.002, pmid:27432545
  25. Junya Toba, Miyu Nikkuni, Masato Ishizeki, Aya Yoshii, Naoto Watamura, Takafumi Inoue, Toshio Ohshima
    PPARγ agonist pioglitazone improves cerebellar dysfunction at pre-Aβ deposition stage in APPswe/PS1dE9 Alzheimer's disease model mice
    Biochemical and Biophysical Research Communications, 473:1039-1044 (2016), doi:10.1016/j.bbrc.2016.04.012, pmid:27059136
  26. Nasrin Shafeghat, Morteza Heidarinejad, Noboru Murata, Hideki Nakamura, Takafumi Inoue
    Optical detection of neuron connectivity by random access two-photon microscopy
    Journal of Neuroscience Methods, 263:48-56 (2016), doi:10.1016/j.jneumeth.2016.01.023, pmid:26851307, postprint
  27. Takanobu Nakazawa, Ryota Hashimoto, Kazuto Sakoori, Yuki Sugaya, Asami Tanimura, Yuki Hashimotodani, Kazutaka Ohi, Hidenaga Yamamori, Yuka Yasuda, Satomi Umeda-Yano, Yuji Kiyama, Kohtarou Konno, Takeshi Inoue, Kazumasa Yokoyama, Takafumi Inoue, Shusuke Numata, Tohru Ohnuma, Nakao Iwata, Norio Ozaki, Hitoshi Hashimoto, Masahiko Watanabe, Toshiya Manabe, Tadashi Yamamoto, Masatoshi Takeda, Masanobu Kano
    Emerging roles of ARHGAP33 in intracellular trafficking of trkB and pathophysiology of neuropsychiatric disorders
    Nature Communications, 7:10594 (2016), doi:10.1038/ncomms10594, pmid:26839058, press release
  28. Xiaohua Jin, Kodai Sasamoto, Jun Nagai, Yuki Yamazaki, Kenta Saito, Yoshio Goshima, Takafumi Inoue, Toshio Ohshima
    Phosphorylation of CRMP2 by Cdk5 regulates dendritic spine development of cortical neuron in the mouse hippocamp
    Neural Plasticity, vol. 2016, Article ID 6790743, 7 pages (2016), doi:10.1155/2016/6790743, pmid:26819770
  29. Mitsumasa Homma, Yoshiaki Takei, Atsushi Miura, Takafumi Inoue, Shinji Takeoka
    A retiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells
    Chemical Communications, 51:6194-6197 (2015), doi:10.1039/C4CC10349A, pmid:25754014
  30. Takafumi Inoue, Keishi Narita, Yuta Nonami, Hideki Nakamura, Sen Takeda
    Observation of the ciliary movement of choroid plexus epithelial cells ex vivo
    The Journal of Visualized Experiments (JoVE), e52991 (2015), doi:10.3791/52991, pmid:26273731
  31. Keishi Narita, Shohei Sasamoto, Schuichi Koizumi, Shizuka Okazaki, Hideki Nakamura, Takafumi Inoue, Sen Takeda
    TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport
    FASEB Journal, 29:2247-2259 (2015), doi:10.1096/fj.14-261396, pmid:25681460
  32. Vinicius Nikolaos Samios, Takafumi Inoue
    Interleukin-1β and interleukin-6 affect electrophysiological properties of thalamic relay cells
    Neuroscience Research, 87:16-25 (2014), doi:10.1016/j.neures.2014.06.011, pmid:25091392, postprint
  33. Haruki Odaka, Satoshi Arai, Takafumi Inoue, Tetsuya Kitaguchi
    Genetically-encoded yellow fluorescent cAMP indicator with expanded dynamic range for dual-color imaging
    PLoS ONE, 9:e100252 (2014), doi:10.1371/journal.pone.0100252, pmid:24959857
  34. Haruki Odaka, Tadahiro Numakawa, Naoki Adachi, Yoshiko Ooshima, Shingo Nakajima, Yusuke Katanuma, Takafumi Inoue, Hiroshi Kunugi
    Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity
    PLoS ONE, 9:e99271 (2014), doi:10.1371/journal.pone.0099271, pmid:24914776
  35. Xiaojuan He, Masato Ishizeki, Naoki Mita, Seitaro Wada, Yoshifumi Araki, Hiroo Ogura, Manabu Abe, Maya Yamazaki, Kenji Sakimura, Katsuhiko Mikoshiba, Takafumi Inoue, Toshio Ohshima
    Cdk5/p35 is required for motor coordination and cerebellar plasticity
    Journal of Neurochemistry, 131:53-64 (2014), doi:10.1111/jnc.12756, pmid:24802945
  36. Yuki Kuwabara, Masato Ishizeki, Naoto Watamura, Junya Toba, Aya Yoshii, Takafumi Inoue, Toshio Ohshima
    Impairments of LTD induction and motor coordination precede Aß accumulation in the cerebellum of APPswe/PS1dE9 double transgenic mice
    Journal of Neurochemistry, 130:432-443 (2014), doi:10.1111/jnc.12728, pmid:24684630
  37. Yusuke Katanuma, Tadahiro Numakawa, Naoki Adachi, Noriko Yamamoto, Yoshiko Ooshima, Haruki Odaka, Takafumi Inoue, Hiroshi Kunugi
    Phencyclidine rapidly decreases neuronal mRNA of brain-derived neurotrophic factor
    Synapse, 68:257-265 (2014), doi:10.1002/syn.21735, pmid:24615983
  38. Yumiko Aoshima, Ryosuke Hokama, Keitaro Sou, Satya Sarker, Kabuto Iida, Hideki Nakamura, Takafumi Inoue, Shinji Takeoka
    Cationic amino acid-based lipids as effective non-viral gene delivery vectors for primary neurons
    ACS Chemical Neuroscience, 4:1514-1519 (2013), doi:10.1021/cn400036j
  39. Yuta Nonami, Keishi Narita, Hideki Nakamura, Takafumi Inoue, Sen Takeda
    Developmental changes in ciliary motility on choroid plexus epithelial cells during the perinatal period
    Cytoskeleton, 70:797-803 (2013), doi:10.1002/cm.21132, pmid:23959957
  40. Yoshiaki Takei, Atsushi Murata, Kento Yamagishi, Satoshi Arai, Hideki Nakamura, Takafumi Inoue, Shinji Takeoka
    Intracellular click reaction with a fluorescent chemical Ca2+ indicator to prolong its cytosolic retention
    Chemical Communications, 49:7313-7315 (2013), doi:10.1039/C3CC42489H, pmid:23851490
  41. Yu-Chun Lin, Benjamin Lin, Pawel Niewiadomski, Hideki Nakamura, Siew Cheng Phua, John Jiao, Takafumi Inoue, Andre Levchenko, Rajat Rohatgi, Takanari Inoue
    Chemically-inducible diffusion trap at cilia (C-IDTc) reveals molecular sieve-like barrier
    Nature Chemical Biology, 9:437-443 (2013), doi:10.1038/nchembio.1252, pmid:23666116
  42. Takafusa Hikichi, Ryo Matoba, Takashi Ikeda, Akira Watanabe, Takuya Yamamoto, Satoko Yoshitake, Miwa Tamura-Nakano, Takayuki Kimura, Masayoshi Kamon, Mari Shimura, Koichi Kawakami, Akihiko Okuda, Hitoshi Okochi, Takafumi Inoue, Atsushi Suzuki, Shinji Masui
    Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles
    Proceedings of the National Academy of Sciences of the United States of America, 110: 6412-6417 (2013), doi:10.1073/pnas.1220200110, pmid:23550161, press release
  43. Satya Ranjan Sarker, Yumiko Aoshima, Ryosuke Hokama, Takafumi Inoue, Keitaro Sou, Shinji Takeoka
    Arginine-based cationic liposomes for efficient in vitro plasmid DNA delivery with low cytotoxicity
    International Journal of Nanomedicine, 2013:8:1361-1375 (2013), doi:10.2147/IJN.S38903, pmid:23630419
  44. Ayumi Kumazawa, Naoki Mita, Motoyuki Hirasawa, Tomoko Adachi, Hiromi Suzuki, Nasrin Shafeghat, Ashok B. Kulkarni, Katsuhiko Mikoshiba, Takafumi Inoue, Toshio Ohshima
    Cyclin-dependent kinase 5 is required for normal cerebellar development
    Molecular and Cellular Neuroscience, 52:97-105 (2013), doi:10.1016/j.mcn.2012.10.007, pmid:23085039
  45. Kristina Leuner, Wei Li, Michelle D. Amaral, Stephanie Rudolph, Gaston Calfa, Anita M. Schuwald, Christian Harteneck, Takafumi Inoue, Lucas Pozzo-Miller
    Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca2+-premeable TRPC6 channels
    Hippocampus, 23:40-52 (2013), doi:10.1002/hipo.22052, pmid:22815087
  46. Sayako Tamamushi, Takeshi Nakamura, Takafumi Inoue, Etsuko Ebisui, Kotomi Sugiura, Hiroko Bannai, Katsuhiko Mikoshiba
    Type 2 inositol 1,4,5-trisphosphate receptor is predominantly involved in agonist-induced Ca2+ signaling in Bergmann glia
    Neuroscience Research, 74:32–41 (2012), doi:10.1016/j.neures.2012.06.005, pmid:22771532
  47. Hikdeki Nakamura, Hiroko Bannai, Takafumi Inoue, Takayuki Michikawa, Masaki Sano, Katsuhiko Mikoshiba
    Cooperative and stochastic calcium releases from multiple calcium puff sites generate calcium microdomains in intact HeLa cells
    Journal of Biological Chemistry, 287:24563-24572 (2012), doi:10.1074/jbc.M111.311399, pmid:22637479
  48. Keishi Narita, Hiroko Kozuka-Hata, Yuta Nonami, Hideki Nakamura, Hiroko Ao-Kondo, Masaaki Oyama, Takafumi Inoue, Sen Takeda
    Proteomics of choroid plexus epithelial cilia reveals unexpected mosaic distribution of heterogeneous cilia in a cellular level
    Biology Open, 1:815-825 (2012), doi:10.1242/bio.20121081, pmid:23213475
  49. Gaston Calfa, Christopher A. Chapleau, Susan Campbell, Takafumi Inoue, Sarah J. Morse, Farah D. Lubin, Lucas Pozzo-Miller
    HDAC activity is required for BDNF to increase quantal neurotransmitter release and dendritic spine density in CA1 pyramidal neurons
    Hippocampus, 22: 1493-1500 (2012), doi:10.1002/hipo.20990, pmid:22161912
  50. Shoichiro Kanda, Yutaka Harita, Yoshio Shibagaki, Takashi Sekine, Takashi Igarashi, Takafumi Inoue, Seisuke Hattori
    Tyrosine phosphorylation-dependent activation of TRPC6 regulated by PLC-γ1 and Nephrin: Effect of mutations associated with focal segmental glomerulosclerosis
    Molecular Biology of the Cell, 22:1824-1835 (2011), doi:10.1091/mbc.E10-12-0929, pmid:21471003
  51. Kazumi Fukatsu, Hiroko Bannai, Takafumi Inoue, Katsuhiko Mikoshiba
    Lateral diffusion of inositol 1,4,5-trisphosphate receptor type 1 in Purkinje cells is regulated by calcium and actin filaments
    Journal of Neurochemistry, 114:1720-1733 (2010), doi:10.1111/j.1471-4159.2010.06885.x, pmid:20626556
  52. Takayuki Matsumura, Masaaki Oyama, Hiroko Kozuka-Hata, Kosuke Ishikawa, Takafumi Inoue, Tatsushi Muta, Kentaro Semba, Jun-ichiro Inoue
    Identification of BCAP-L as a negative regulator of TLR signaling-induced production of IL-6 and IL-10 in macrophages by tyrosine phosphoproteomics
    Biochemical and Biophysical Research Communications, 400:265-270 (2010), doi:10.1016/j.bbrc.2010.08.055, pmid:20728433
  53. Nicholas K. H. Khoo, C. Roger White, Lucas Pozzo-Miller, Fen Zhou, Chad Constance, Takafumi Inoue, Rakesh P. Patel, Dale A. Parks
    Dietary flavonoid quercetin stimulates vasorelaxation in aortic vessels
    Free Radical Biology & Medicine, 49:339-347 (2010), doi:10.1016/j.freeradbiomed.2010.04.022, pmid:20423726
  54. Yong Li, Gaston Calfa, Takafumi Inoue, Michelle Amaral, Lucas Pozzo-Miller
    Activity-dependent release of endogenous BDNF from mossy fibers evokes a TRPC3 current and Ca2+ elevations in CA3 pyramidal neurons
    Journal of Neurophysiology, 103:2846-2856 (2010), doi:10.1152/jn.01140.2009, pmid:20220070
  55. Kiyoshi Katsumata, Jun Nishiyama, Takafumi Inoue, Noboru Mizushima, Junzo Takeda, Michisuke Yuzaki
    Dynein- and activity-dependent retrograde transport of autophagosomes in neuronal axons
    Autophagy, 6:378-385 (2010), doi:10.4161/auto.6.3.11262, pmid: 20150763
  56. Sachiko Taniguchi, Takanobu Nakazawa, Asami Tanimura, Yuji Kiyama, Tohru Tezuka, Ayako M. Watabe, Norikazu Katayama, Kazumasa Yokoyama, Takeshi Inoue, Hiroko Izumi-Nakaseko, Shigeru Kakuta, Katsuko Sudo, Yoichiro Iwakura, Hisashi Umemori, Takafumi Inoue, Niall P. Murphy, Kouichi Hashimoto, Masanobu Kano, Toshiya Manabe, Tadashi Yamamoto
    Involvement of NMDAR2A tyrosine phosphorylation in depression-related behavior
    EMBO Journal, 28:3717-3729 (2009), doi:10.1038/emboj.2009.300, pmid:19834457
  57. Hiroko Bannai, Sabine Lévi, Claude Schweizer, Takafumi Inoue, Thomas Launey, Victor Racine, Jean-Baptiste Sibarita, Katsuhiko Mikoshiba, Antoine Triller
    Activity-dependent tuning of inhibitory neurotransmission based on GABAAR diffusion dynamics
    Neuron, 62:670-682 (2009), doi:10.1016/j.neuron.2009.04.023, pmid:19524526
  58. Kogiku Shiba, Shoji A. Baba, Takafumi Inoue, Manabu Yoshida
    Ca2+ bursts occur around a local minimal concentration of attractant and trigger sperm chemotactic response
    Proceedings of the National Academy of Sciences of the United States of America    , 105:19311-19316 (2008), doi:10.1073/pnas.0808580105, pmid:19047630, press release
  59. Chihiro Hisatsune, Yukiko Kuroda, Takumi Akagi, Takashi Torashima, Hirokazu Hirai, Tsutomu Hashikawa, Takafumi Inoue, Katsuhiko Mikoshiba
    Inositol 1, 4, 5-trisphosphate receptor type 1 in granule cells, not in Purkinje cells, regulates the dendritic morphology of Purkinje cells through brain-derived neurotrophic factor production
    The Journal of Neuroscience    , 26:10916-10924 (2006), doi:10.1523/JNEUROSCI.3269-06.2006, pmid:17050730
  60. Toru Matsu-ura, Takayuki Michikawa, Takafumi Inoue, Atsushi Miyawaki, Manabu Yoshida, Katsuhiko Mikoshiba
    Cytosolic inositol 1,4,5-trisphosphate dynamics during intracellular calcium oscillations in living cells
    The Journal of Cell Biology    , 173:755-765 (2006), doi:10.1083/jcb.200512141, pmid:16754959
  61. Kazumi Fukatsu, Hiroko Bannai, Takafumi Inoue, Katsuhiko Mikoshiba
    4.1N binding regions of inositol 1,4,5-trisphosphate receptor type 1
    Biochemical and Biophysical Research Communications    , 342:573-576 (2006), doi:10.1016/j.bbrc.2006.02.010, pmid:16487933
  62. Jun-Ichi Goto, Takafumi Inoue, Akinori Kuruma, Katsuhiko Mikoshiba
    Short-term potentiation at the parallel fiber-Purkinje cell synapse
    Neuroscience Research    , 55:28-33 (2006), doi:10.1016/j.neures.2006.01.001, pmid:16472880
  63. Hiroaki Kodama, Takafumi Inoue, Ryuichi Watanabe, Daisuke Yasutomi, Yutaka Kawakami, Satoshi Ogawa, Katsuhiko Mikoshiba, Yasuo Ikeda, Masataka Kuwana
    Neurogenic potential of progenitors derived from human circulating CD14+ monocytes
    Immunology and Cell Biology    , 84:209-217 (2006), doi:10.1111/j.1440-1711.2006.01424.x, pmid:16519739
  64. Hiroaki Kodama, Takafumi Inoue, Ryuichi Watanabe, Hidekata Yasuoka, Yutaka Kawakami, Satoshi Ogawa, Yasuo Ikeda, Katsuhiko Mikoshiba, Masataka Kuwana
    Cardiomyogenic potential of mesenchymal progenitors derived from human circulating CD14+ monocytes
    Stem Cells and Development    , 14:676-686 (2005), doi:10.1089/scd.2005.14.676, pmid:16433623
  65. Miwako Iwai, Yoko Tateishi, Mitsuharu Hattori, Akihiro Mizutani, Takeshi Nakamura, Akira Futatsugi, Takafumi Inoue, Teiichi Furuichi, Takayuki Michikawa, Katsuhiko Mikoshiba
    Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant
    Journal of Biological Chemistry    , 280:10305-10317 (2005), doi:10.1074/jbc.M413824200, pmid:15632133
  66. Yoko Tateishi, Mitsuharu Hattori, Tomohiro Nakayama, Miwako Iwai, Hiroko Bannai, Takeshi Nakamura, Takayuki Michikawa, Takafumi Inoue, Katsuhiko Mikoshiba
    Cluster formation of inositol 1,4,5-trisphosphate receptor requires its transition to open state
    Journal of Biological Chemistry    , 280:6816-6822 (2005), doi:10.1074/jbc.M405469200, pmid:15583010
  67. Keishi Otsu, Akinori Kuruma, Eri Yanagida, Satoshi Shoji, Takafumi Inoue, Yoshiyuki Hirayama, Hiroshi Uematsu, Yukichi Hara, Seiko Kawano
    Na+/K+ ATPase and its functional couplings with Na+/Ca2+ exchangers in mouse embryonic stem cells during differentiation into cardiomyocytes
    Cell Calcium    , 37:137-151 (2005), doi:10.1016/j.ceca.2004.08.004, pmid:15589994
  68. Hiroko Bannai, Kazumi Fukatsu, Akihiro Mizutani, Tohru Natsume, Shin-ichiro Iemura, Tohru Ikegami, Takafumi Inoue, Katsuhiko Mikoshiba
    An RNA-interacting protein SYNCRIP (heterogeneous nuclear ribonuclear protein Q1/NSAP1) is a component of mRNA granule transported with inositol 1,4,5-trisphosphate receptor type 1 mRNA in neuronal dendrites
    Journal of Biological Chemistry    , 279:53427-53434 (2004), doi:10.1074/jbc.M409732200, pmid:15475564
  69. Kazumi Fukatsu, Hiroko Bannai, Songbai Zhang, Hideki Nakamura, Takafumi Inoue, Katsuhiko Mikoshiba
    Lateral diffusion of inositol 1,4,5-trisphosphate receptor type 1 is regulated by actin filaments and 4.1N in neuronal dendrites
    Journal of Biological Chemistry    , 279:48976-48982 (2004), doi:10.1074/jbc.M408364200, pmid:15364918
  70. Iskandar Ismailov, Djanenkhodja Kalikulov, Takafumi Inoue, Michael J. Friedlander
    The kinetic profile of intracellular calcium predicts long-term potentiation and long-term depression
    The Journal of Neuroscience    , 24:9847-9861 (2004), doi:10.1523/JNEUROSCI.0738-04.2004, pmid:15525769
  71. Kristi A. Kohlmeier, Takafumi Inoue, Christopher S. Leonard
    Hypocretin/Orexin peptide signaling in the ascending arousal system: Elevation of intracellular calcium in the mouse dorsal raphe and laterodorsal tegmentum
    Journal of Neurophysiology    , 92:221-235 (2004), doi:10.1152/jn.00076.2004, pmid:14999052
  72. Weihua Cai, Chihiro Hisatsune, Kyoko Nakamura, Takeshi Nakamura, Takafumi Inoue, Katsuhiko Mikoshiba
    Activity-dependent expression of inositol 1,4,5-trisphosphate receptor type 1 in hippocampal neurons
    Journal of Biological Chemistry    , 279:23691-23698 (2004), doi:10.1074/jbc.M313296200, pmid:15016804
  73. Chihiro Hisatsune, Yukiko Kuroda, Kyoko Nakamura, Takafumi Inoue, Takeshi Nakamura, Takayuki Michikawa, Akihiro Mizutani, Katsuhiko Mikoshiba
    Regulation of TRPC6 channel activity by tyrosine phosphorylation
    Journal of Biological Chemistry, 279:18887-18894 (2004), doi:10.1074/jbc.M311274200, pmid:14761972
  74. Mitsuharu Hattori, Akinobu Z. Suzuki, Takayasu Higo, Hiroshi Miyauchi, Takayuki Michikawa, Takeshi Nakamura, Takafumi Inoue, Katsuhiko Mikoshiba
    Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling
    Journal of Biological Chemistry, 279:11967-11975 (2004), doi:10.1074/jbc.M311456200, pmid:14707143
  75. Tomohiro Nakayama, Mitsuharu Hattori, Keiko Uchida, Takeshi Nakamura, Yoko Tateishi, Hiroko Bannai, Miwako Iwai, Takayuki Michikawa, Takafumi Inoue, Katsuhiko Mikoshiba
    The regulatory domain of the inositol 1,4,5-trisphosphate receptor is necessary to keep the channel domain closed: Possible physiological significance of specific cleavage by caspase 3
    Biochemical Journal    , 377:299-307 (2004), doi:10.1042/BJ20030599, pmid:12968951
  76. Hiroko Bannai, Takafumi Inoue, Tomohiro Nakayama, Mitsuharu Hattori, Katsuhiko Mikoshiba
    Kinesin dependent, rapid, bidirectional transport of inositol-1,4,5-trisphosphate receptor containing particles in the dendrite of hippocampal neurons
    Journal of Cell Science    , 117:163-175 (2004), doi:10.1242/​jcs.00854, pmid:14676272
  77. Akinori Kuruma, Takafumi Inoue, Katsuhiko Mikoshiba
    Dynamics of Ca2+ and Na+ in the dendrite of mouse cerebellar Purkinje cells evoked by parallel fiber stimulation
    European Journal of Neuroscience    , 18:2677-2689 (2003), doi:10.1111/j.1460-9568.2003.02977.x, pmid:14656316
  78. Takafumi Inoue
    Dynamics of calcium and its roles in the dendrite of cerebellar Purkinje cell
    The Keio Journal of Medicine, 52:244-249 (2003), doi:110.2302/kjm.52.244
  79. Kiyoko Fukami, Takafumi Inoue, Manabu Kurokawa, Rafael A. Fissore, Kazuki Nakao, Kohji Nagano, Yoshikazu Nakamura, Kei Takenaka, Nobuaki Yoshida, Katuhiko Mikoshiba, Tadaomi Takenawa
    Phospholipase Cδ4: from genome structure to physiological function
    Advances in Enzyme Regulation, 43:87-106 (2003), doi:10.1016/S0065-2571(02)00029-8
  80. Kiyoko Fukami, Manabu Yoshida, Takafumi Inoue, Manabu Kurokawa, Rafael A. Fissore, Nobuaki Yoshida, Katsuhiko Mikoshiba, Tadaomi Takenawa
    Phospholipase Cδ4 is required for Ca2+-mobilization essential for acrosome reaction in sperm
    The Journal of Cell Biology, 161:79-88 (2003), doi:10.1083/jcb.200210057, pmid:12695499
  81. Yukinori Minoshima, Toshiyuki Kawashima, Koichi Hirose, Yukio Tonozuka, Aie Kawajiri, Ying Chun Bao, Xingming Deng, Masaaki Tatsuka, Shuh Narumiya, W. Stratford May Jr., Tetsuya Nosaka, Kentaro Semba, Takafumi Inoue, Takaya Satoh, Masaki Inagaki, Toshio Kitamura
    Phosphorylation by Aurora B converts MgcRacGAP to a RhoGAP during cytokinesis
    Developmental Cell, 4:549-560 (2003), doi:10.1016/S1534-5807(03)00089-3, pmid:12689593
  82. T. Nagase, K-I. Ito, K. Kato, K. Kaneko, K. Kohda, M. Matsumoto, A. Hoshino, T. Inoue, S. Fujii, H. Kato, K. Mikoshiba
    Long-term potentiation and long-term depression in hippocampal CA1 neurons of mice lacking the IP3 type 1 receptor
    Neuroscience, 117:821-830 (2003), doi:10.1016/S0306-4522(02)00803-5, pmid:12654335
  83. Hiroki Yasuda, Hideyoshi Higashi, Yoshihisa Kudo, Takafumi Inoue, Yoshio Hata, Katsuhiko Mikoshiba, Tadaharu Tsumoto
    Imaging of calcineurin activated by long-term depression-inducing synaptic inputs in living neurons of rat visual cortex
    European Journal of Neuroscience    , 17:287-297 (2003), doi:10.1046/j.1460-9568.2003.02449.x, pmid:12542665
  84. Yuko Aihara, Takafumi Inoue, Tomoko Tashiro, Koichi Okamoto, Yoshiaki Komiya, Katsuhiko Mikoshiba
    Movement of endoplasmic reticulum in the living axon is distinct from other membranous vesicles in its rate, form, and sensitivity to microtubule inhibitors
    Journal of Neuroscience Research    , 65:236-246 (2001), doi:10.1002/jnr.1147, pmid:11494358
  85. Kiyoko Fukami, Kazuki Nakao, Takafumi Inoue, Yuki Kataoka, Manabu Kurokawa, Rafael A. Fissore, Kenji Nakamura, Motoya Katsuki, Katsuhiko Mikoshiba, Nobuaki Yoshida, Tadaomi Takenawa
    Requirement of phospholipase Cδ4 for the zona pellucida-induced acrosome reaction
    Science    , 292:920-923 (2001), doi:10.1126/science.1059042, pmid:11340203
  86. Takafumi Inoue, Xi Lin, Kristi A. Kohlmeier, Harry T. Orr, Huda Y. Zoghbi, William N. Ross
    Calcium dynamics and electrophysiological properties of cerebellar Purkinje cells in SCA1 transgenic mice
    Journal of Neurophysiology    , 85:1750-1760 (2001), doi:10.1152/jn.2001.85.4.1750, pmid:11287496
  87. Shoen Kume, Takafumi Inoue, Katsuhiko Mikoshiba
    Gαs family G proteins activate IP3- Ca2+ signaling via Gβγ and transduce ventralizing signals in Xenopus
    Developmental Biology    , 226:88-103 (2000), doi:10.1006/dbio.2000.9849, pmid:10993676
  88. Christopher S. Leonard, Sanjai R. Rao, Takafumi Inoue
    Serotonergic inhibition of action potential evoked calcium transients in NOS-containing mesopontine cholinergic neurons
    Journal of Neurophysiology    , 84:1558-1572 (2000), doi:10.1152/jn.2000.84.3.1558, pmid:10980027
  89. Lucas D. Pozzo-Miller, Takafumi Inoue, Diane DiEuliis Murphy
    Estradiol increases spine density and NMDA-dependent Ca2+ transients in spines of CA1 pyramidal neurons from hippocampal slices
    Journal of Neurophysiology    , 81:1404-1411 (1999), doi:10.1152/jn.1999.81.3.1404, pmid:10085365
  90. Hisashi Umemori, Takashi Hayashi, Takafumi Inoue, Shigetada Nakanishi, Katsuhiko Mikoshiba, Tadashi Yamamoto
    Involvement of protein tyrosine phosphatases in activation of the trimeric G protein Gq/11
    Oncogene, 18:7399-7402 (1999), doi:10.1038/sj.onc.1203152, pmid:10602498
  91. Matsuhiko Hayashi, Toshiaki Monkawa, Tadashi Yoshida, Hiroyuki Sasamura, Mineo Matsumoto, Takafumi Inoue, Katsuhiko Mikoshiba, Takao Saruta
    Intracellular calcium concentration in the inositol trisphosphate receptor type 1 knockout mouse
    Journal of the American Society of Nephrology    , 10:2094-2101 (1999), pmid:10505685
  92. Takafumi Inoue, Kunio Kato, Kazuhisa Kohda, Katsuhiko Mikoshiba
    Type 1 inositol 1,4,5-trisphosphate receptor is required for induction of long-term depression in cerebellar Purkinje neurons
    The Journal of Neuroscience    , 18:5366-5373 (1998), doi:10.1523/JNEUROSCI.18-14-05366.1998, pmid:9651219
  93. Kohtaro Takei, Ryong-Moon Shin, Takafumi Inoue, Kunio Kato, Katsuhiko Mikoshiba
    Regulation of nerve growth mediated by inositol 1,4,5-trisphosphate receptors in growth cones
    Science    , 282:1705-1708 (1998), doi:10.1126/science.282.5394.1705, pmid:9831561
  94. Manabu Yoshida, Noburu Sensui, Takafumi Inoue, Masaaki Morisawa, Katsuhiko Mikoshiba
    Role of two series of Ca2+ oscillation in activation of ascidian eggs
    Developmental Biology, 203:122-133 (1998), doi:10.1006/dbio.1998.9037, pmid:9806778
  95. Shoen Kume, Akira Muto, Takafumi Inoue, Kei Suga, Hideyuki Okano, Katsuhiko Mikoshiba
    Role of inositol 1,4,5-trisphosphate receptor in ventral signaling in Xenopus embryos
    Science    , 278:1940-1943 (1997), doi:10.1126/science.278.5345.1940, pmid:9395395
  96. Hisashi Umemori, Takafumi Inoue, Shoen Kume, Naohiro Sekiyama, Motoshi Nagao, Hiroshi Itoh, Shigetada Nakanishi, Katsuhiko Mikoshiba, Tadashi Yamamoto
    Activation of the G protein Gq/11 through tyrosine phosphorylation of the α subunit
    Science    , 276:1878-1881 (1997), doi:10.1126/science.276.5320.1878, pmid:9188537
  97. Chihiro Hisatsune, Hisashi Umemori, Takafumi Inoue, Takayuki Michikawa, Kazuhisa Kohda, Katsuhiko Mikoshiba, Tadashi Yamamoto
    Phosphorylation-dependent regulation of N-methyl-D-aspartate receptors by calmodulin
    Journal of Biological Chemistry, 272:20805-20810 (1997), doi:10.1074/jbc.272.33.20805, pmid:9252405
  98. Shoen Kume, Akitsugu Yamamoto, Takafumi Inoue, Akira Muto, Hideyuki Okano, Katsuhiko Mikoshiba
    Developmental expression of the inositol 1,4,5-trisphosphate receptor and structural changes in the endoplasmic reticulum during oogenesis and meiotic maturation of Xenopus laevis
    Developmental Biology    , 182:228-239 (1997), doi:10.1006/dbio.1996.8479, pmid:9070324
  99. M. Matsumoto, T. Nakagawa, T. Inoue, E. Nagata, K. Tanaka, H. Takano, O. Minowa, J. Kuno, S. Sakakibara, M. Yamada, H. Yoneshima, A. Miyawaki, Y. Fukuuchi, T. Furuichi, H. Okano, K. Mikoshiba, T. Noda
    Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor
    Nature    , 379:168-171(1996), doi:10.1038/379168a0, pmid:8538767
  100. Akira Muto, Shoen Kume, Takafumi Inoue, Hideyuki Okano, Katsuhiko Mikoshiba
    Calcium waves along the cleavage furrows in cleavage-stage Xenopus embryos and its inhibition by heparin
    The Journal of Cell Biology    , 135:181-190 (1996), doi:10.1083/jcb.135.1.181, pmid:8858172
  101. J. M. Matheson, A. Miyawaki, A. Muto, T. Inoue, K. Mikoshiba
    Expression of the green fluorescent protein derivative S65T in Xenopus laevis oocytes
    Biomedical Research    , 17:221-225 (1996), doi:10.1016/S0076-6879(99)02022-4, pmid:12876775
  102. Kazuhisa Kohda, Takafumi Inoue, Katsuhiko Mikoshiba
    Ca2+ release from Ca2+ stores, particularly from ryanodine-sensitive Ca2+ stores, is required for the induction of LTD in cultured cerebellar Purkinje cells
    Journal of Neurophysiology    , 74:2184-2188 (1995), doi:10.1152/jn.1995.74.5.2184, pmid:8592207
  103. Ken-ichi Ito, Masami Miura, Hidekazu Furuse, Chen Zhixiong, Hiroshi Kato, Daisuke Yasutomi, Takafumi Inoue, Katsuhiko Mikoshiba, Tetsutoshi Kimura, Shunpei Sakakibara, Hiroyoshi Miyakawa
    Voltage-gated channel Ca2+ blockers, ω-AgaIVA and Ni2+, suppress the induction of θ-burst induced long-term potentiation in guinea-pig hippocampal CA1 neurons
    Neuroscience Letters    , 183:112-115 (1995), doi: 10.1016/0304-3940(94)11127-5, pmid:7746467
  104. Takafumi Inoue, Hiroyoshi Miyakawa, Ken-ichi Ito, Katsuhiko Mikoshiba, Hiroshi Kato
    A hyperpolarizing response induced by glutamate in mouse cerebellar Purkinje cells
    Neuroscience Research    , 15:265-271 (1992),doi: 10.1016/0168-0102(92)90047-g, pmid:1363130, pmid:1363130
  105. Takafumi Inoue, Taka-aki Tamura, Teiichi Furuichi, Katsuhiko Mikoshiba
    Isolation of complementary DNAs encoding a cerebellum-enriched nuclear factor I family that activates transcription from the mouse myelin basic protein promoter
    Journal of Biological Chemistry, 265:19065-19070 (1990), pmid:1699939
  106. Taka-aki Tamura, Atsuo Aoyama, Takafumi Inoue, Masayuki Miura, Katsuhiko Mikoshiba
    A new transcription element in the JC virus enhancer
    Journal of General Virology, 71:1829-1833 (1990), doi:10.1099/0022-1317-71-8-1829, pmid:2167938
  107. Taka-aki Tamura, Yasuko Ohya, Masayuki Miura, Atsuo Aoyama, Takafumi Inoue, Katsuhiko Mikoshiba
    Preparation of large amounts of transcription-competent nuclear extracts from mouse brain
    Technique    , 1:33-36 (1989)
  108. Taka-aki Tamura, Atsuo Aoyama, Takafumi Inoue, Masayuki Miura, Hideyuki Okano, Katsuhiko Mikoshiba
    Tissue-specific in vitro transcription from the mouse myelin basic protein promoter
    Molecular and Cellular Biology    , 9:3122-3126 (1989), doi:10.1128/MCB.9.7.3122, pmid:2476662
  109. Taka-aki Tamura, Takafumi Inoue, Kyosuke Nagata, Katsuhiko Mikoshiba
    Enhancer of human polyoma JC virus contains nuclear factor I-binding sequences; Analysis using mouse brain nuclear extracts
    Biochemical and Biophysical Research Communications    , 157:419-425 (1988), doi:10.1016/S0006-291X(88)80265-1, pmid:2849429